MICRB 450Bacterial Genetics
Emphasis will be on the role of mutations in the analysis of gene function; a detailed analysis of replication, transcription, translation, recombination and DNA repair. The course will also delve into the mechanisms involved in the regulation of gene expression both at the individual gene level as well as on a "global" scale. The course will examine the structure, replication and utilization of plasmids, transposons and bacteriophages, particularly focusing on their roles in the horizontal transfer of DNA between bacteria. The course will include both formal lecture presentations by the instructor as well as presentations of published research related to the field of bacterial genetics whenever possible.